Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28524774 | 0.91 | CHRM2 (0.68) | CHRM2ACHEKDM4EALDH1A1CHRM4 | |
| SCHEMBL28204839 | 0.82 | CHRM2 (0.85) | CHRM2CHRM3 | |
| SCHEMBL28136567 | 0.82 | CHRM2 (0.39) | CHRM2ACHEKDM4EALDH1A1CHRM4 | |
| Carbamic Acid SCHEMBL29018025 | 0.80 | CHRM2 (0.69) | CHRM2ACHEKDM4EALDH1A1CHRM4 | |
| SCHEMBL28524727 | 0.80 | CHRM2 (0.53) | CHRM2ACHECHRM4OPRM1OPRD1 | |
| SCHEMBL28896706 | 0.78 | CHRM2 (0.60) | CHRM2ACHEKDM4EALDH1A1NPC1 | |
| SCHEMBL28521333 | 0.78 | CHRM2 (0.51) | CHRM2ACHECHRM4OPRM1OPRD1 | |
| SCHEMBL6021912 | 0.77 | CHRM2 (0.56) | CHRM2ACHEKDM4EALDH1A1CHRM4 | |
| SCHEMBL29018251 | 0.77 | CHRM2 (0.72) | CHRM2ACHEKDM4EALDH1A1NPC1 | |
| SCHEMBL28953805 | 0.76 | CHRM2 (0.67) | CHRM2ACHEKDM4EALDH1A1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107849047-A | Biphenyl derivative, preparation method and medical application thereof | 四川海思科制药有限公司 | 2018-03-27 | — | — | CN | disclosed |