Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.77 |
| ▸ | CHRM3 | P20309 | 19/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28204778 | 1.00 | CHRM2 (0.77) | CHRM2CHRM3ADRB2 | |
| SCHEMBL28204774 | 1.00 | CHRM2 (0.77) | CHRM2CHRM3ADRB2 | |
| SCHEMBL31221643 | 0.92 | CHRM2 (0.88) | CHRM2CHRM3ADRB2 | |
| SCHEMBL942211 | 0.92 | CHRM2 (0.88) | CHRM2CHRM3ADRB2 | |
| SCHEMBL943273 | 0.89 | CHRM2 (0.85) | CHRM2CHRM3ADRB2 | |
| SCHEMBL643486 | 0.88 | CHRM2 (0.77) | CHRM2CHRM3ADRB2 | |
| SCHEMBL24274186 | 0.88 | CHRM2 (0.87) | CHRM2CHRM3ADRB2 | |
| SCHEMBL10015122 | 0.88 | CHRM2 (0.87) | CHRM2CHRM3ADRB2 | |
| SCHEMBL19154410 | 0.88 | CHRM2 (0.84) | CHRM2CHRM3ADRB2 | |
| SCHEMBL942926 | 0.88 | CHRM2 (0.84) | CHRM2CHRM3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107849047-B | Biphenyl derivative, preparation method and medical application thereof | 四川海思科制药有限公司 | 2021-01-15 | — | — | CN | disclosed |
| CN-107849047-A | Biphenyl derivative, preparation method and medical application thereof | 四川海思科制药有限公司 | 2018-03-27 | — | — | CN | disclosed |