Pyrene

Pyrene

SCHEMBL28205462

NC(Cc1ccccc1)C(=O)O.c1cc2ccc3cccc4ccc(c1)c2c34

nearest known ligand 0.76

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 6/20 0.76
▸ ALPI P09923 1/20 0.76
▸ PKM P14618 1/20 0.76
▸ PTGS1 P23219 1/20 0.76
▸ XIAP P98170 1/20 0.76
▸ SLC1A3 P43003 2/20 0.56
▸ SLC1A2 P43004 2/20 0.56
▸ SLC1A1 P43005 2/20 0.56
▸ NOS3 P29474 3/20 0.55
▸ NOS1 P29475 3/20 0.55
▸ NOS2 P35228 3/20 0.55
▸ GRIA2 P42262 1/20 0.53
▸ SLC15A1 P46059 1/20 0.51
▸ TPH1 P17752 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Phenylalanine SCHEMBL27502165 0.89 SLC7A5 (0.88) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL17553136 0.88 SLC7A5 (0.58) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL19367929 0.88 SLC7A5 (0.58) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL1332173 0.87 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL2785094 0.87 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL23159186 0.87 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL8835931 0.87 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL288606 0.87 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL1330932 0.87 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL1331777 0.87 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110180022-B Shear force response supramolecular bionic articular cartilage material with dynamic lubrication self-repair capacity and preparation method thereof 吉林大学 2021-11-05 — — CN claimed
CN-107670104-B Preparation method of self-lubricating bionic articular cartilage with shear force response 吉林大学 2020-07-03 — — CN claimed
CN-110180022-A A kind of shearing force-responsive supermolecule bionic joint cartilage material and preparation method thereof with dynamically lubricating self-reparing capability 吉林大学 2019-08-30 — — CN claimed
CN-107670104-A A kind of preparation method with shearing force-responsive self-lubricating bionic joint cartilage 吉林大学 2018-02-09 — — CN claimed
CN-107670104-B Preparation method of self-lubricating bionic articular cartilage with shear force response 吉林大学 2020-07-03 — — CN disclosed
CN-107670104-A A kind of preparation method with shearing force-responsive self-lubricating bionic joint cartilage 吉林大学 2018-02-09 — — CN disclosed
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