Benzophenone

Benzophenone

SCHEMBL28206142

CC(N)C(=O)NC(CCCCN)C(=O)O.O=C(c1ccccc1)c1ccccc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ERAP2 Q6P179 4/20 0.47
LNPEP Q9UIQ6 4/20 0.47
ERAP1 Q9NZ08 3/20 0.47
PLG P00747 1/20 0.47
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
CPB1 P15086 1/20 0.45
CPB2 Q96IY4 1/20 0.45
FOLH1 Q04609 1/20 0.45
NOD1 Q9Y239 1/20 0.44
GHSR Q92847 1/20 0.44
TLR2 O60603 1/20 0.44
GNPAT O15228 1/20 0.44
MME P08473 1/20 0.44
ECE1 P42892 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28095115 0.89 FOLH1 (0.54) ERAP2LNPEPERAP1MMP2MMP9
SCHEMBL29511099 0.86 FOLH1 (0.57) ERAP2LNPEPERAP1CPB2FOLH1
SCHEMBL29368554 0.86 FOLH1 (0.57) ERAP2LNPEPERAP1CPB2FOLH1
SCHEMBL1711242 0.86 FOLH1 (0.57) ERAP2LNPEPERAP1CPB2FOLH1
SCHEMBL29563714 0.86 FOLH1 (0.57) ERAP2LNPEPERAP1CPB2FOLH1
SCHEMBL1711244 0.86 FOLH1 (0.57) ERAP2LNPEPERAP1CPB2FOLH1
SCHEMBL1711458 0.85 GNPAT (0.62) ERAP2LNPEPMMP2CPB2GHSR
SCHEMBL1711233 0.85 GNPAT (0.62) ERAP2LNPEPMMP2CPB2GHSR
SCHEMBL31254405 0.85 GNPAT (0.62) ERAP2LNPEPMMP2CPB2GHSR
SCHEMBL1711453 0.85 GNPAT (0.62) ERAP2LNPEPMMP2CPB2GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107677834-A The detection method of TAFIa contents, the kit for detecting TAFIa contents and the application of the two 辽宁迈迪生物科技股份有限公司 2018-02-09 CN claimed
CN-107677834-B The application of the detection method of TAFIa content, the kit for detecting TAFIa content and the two 辽宁迈迪生物科技股份有限公司 2019-07-09 CN disclosed
CN-107677834-A The detection method of TAFIa contents, the kit for detecting TAFIa contents and the application of the two 辽宁迈迪生物科技股份有限公司 2018-02-09 CN disclosed