⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27795422 | 0.64 | — | — | |
| SCHEMBL650558 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL28058999 | 0.62 | — | — | |
| SCHEMBL28295816 | 0.59 | — | — | |
| SCHEMBL1819552 | 0.59 | — | — | |
| SCHEMBL24519738 | 0.58 | — | — | |
| SCHEMBL11227545 | 0.58 | — | — | |
| SCHEMBL26639103 | 0.58 | — | — | |
| SCHEMBL3277667 | 0.58 | — | — | |
| SCHEMBL969789 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110072863-A | RIP1 kinase inhibitors and methods of use | 豪夫迈·罗氏有限公司 | 2019-07-30 | — | — | CN | claimed |
| CN-114728962-A | Plasma kallikrein inhibitors and uses thereof | 武田药品工业有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-110072863-A | RIP1 kinase inhibitors and methods of use | 豪夫迈·罗氏有限公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-110023313-A | Bicyclic amide compound and its application method | 豪夫迈·罗氏有限公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-109843886-A | Two ring pyridone lactams and its application method | 豪夫迈·罗氏有限公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-107849023-A | Bicyclic lactams and methods of use thereof | 豪夫迈·罗氏有限公司 | 2018-03-27 | — | — | CN | disclosed |