Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14690388 | 0.87 | KMT2A (0.48) | MEN1KMT2AHSD17B10HDAC8HDAC3 | |
| SCHEMBL16120763 | 0.82 | CA12 (0.45) | MEN1KMT2AHSD17B10ALDH1A1MAPT | |
| SCHEMBL27655259 | 0.82 | SMN1; SMN2 (0.50) | MEN1KMT2AHDAC8HDAC3HDAC4 | |
| SCHEMBL26032798 | 0.81 | MEN1 (0.51) | CDC25AMEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL12192029 | 0.80 | MEN1 (0.50) | MEN1KMT2AHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL16039148 | 0.79 | MEN1 (0.69) | MEN1KMT2AHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL16039147 | 0.79 | MEN1 (0.69) | MEN1KMT2AHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL29260878 | 0.78 | MEN1 (0.53) | CDC25AMEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL30350633 | 0.78 | MEN1 (0.53) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL19510895 | 0.78 | MEN1 (0.53) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2194139-A1 | Biochemical synthesis of 6 amino caproic acid | DSM IP Assets B.V. (NL) | 2010-06-09 | — | — | EP | disclosed |
| EP-1706501-B1 | BIOCHEMICAL SYNTHESIS OF 6-AMINO CAPROIC ACID | DSM IP ASSETS BV (NL) | 2010-01-13 | — | — | EP | disclosed |
| US-20090137759-A1 | Biochemical synthesis of 6-amino caproic acid | DSM IP ASSETS B.V. (NL) | 2009-05-28 | — | — | US | disclosed |
| US-7491520-B2 | by organism cell biosynthesis from 6-aminohex-2-enoic acid or transform 6-amino-2-hydroxy-hexanoic acid to 6-aminohex-2-enoic acid, in presence of an enzyme having alpha , beta -enoate reductase; chemical intermediates for nylon-6 production | DSM IP ASSETS B.V. (NL) | 2009-02-17 | — | — | US | disclosed |
| US-20070254341-A1 | Biochemical Synthesis of 6-Amino Caproic Acid | GENOMATICA, INC. | 2007-11-01 | — | — | US | disclosed |
| EP-1706501-A2 | BIOCHEMICAL SYNTHESIS OF 6-AMINO CAPROIC ACID | DSM IP Assets B.V. (NL) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005068643-A2 | BIOCHEMICAL SYNTHESIS OF 6-AMINO CAPROIC ACID | DSM IP ASSETS B.V. (NL) | 2005-07-28 | — | — | WO | disclosed |