SCHEMBL28207488

SCHEMBL28207488

O=CC1C=Cc2ncccc2N1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.34
TRIM24 O15164 1/20 0.30
TRIM33 Q9UPN9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20651273 0.74 GSK3B (0.33) GSK3B
SCHEMBL18871859 0.74 GSK3B (0.40) GSK3B
SCHEMBL18323915 0.74 GSK3B (0.40) GSK3B
SCHEMBL27773502 0.73 GSK3B (0.34) GSK3BTRIM24TRIM33
SCHEMBL29995515 0.70 GSK3B (0.31) GSK3B
SCHEMBL15973037 0.69 GSK3B (0.30) GSK3B
SCHEMBL12324881 0.67 GSK3B (0.35) GSK3B
SCHEMBL28264402 0.65
SCHEMBL27762286 0.63 GSK3B (0.47) GSK3BTRIM24TRIM33
SCHEMBL13766039 0.61 GSK3B (0.35) GSK3BTRIM24TRIM33

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109121397-A Heterocyclic compound, especially 2- oxo -4,4,5,5,6,6,7,7- octahydro benzoxazoles derivatives and their purposes as antimicrobial compound 莱德克斯制药公共有限公司 2019-01-01 CN disclosed
CN-107873031-A Benzoxazinone derivatives and analogs thereof as modulators of TNF activity UCB生物制药私人有限公司 2018-04-03 CN disclosed