SCHEMBL28208191

SCHEMBL28208191

COP(=O)(OC)OCc1ccccc1Cl

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.53
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
HDAC8 Q9BY41 2/20 0.41
NR4A2 P43354 2/20 0.41
PNMT P11086 1/20 0.39
PKM P14618 1/20 0.39
KMT2A Q03164 1/20 0.39
MAPT P10636 3/20 0.38
RAB9A P51151 2/20 0.38
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TAAR1 Q96RJ0 2/20 0.38
NPC1 O15118 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9550962 0.89 IDO1 (0.55) IDO1MAOAMAOBHDAC8NR4A2
SCHEMBL11586512 0.84 IDO1 (0.47) IDO1MAOAMAOBNR4A2PNMT
SCHEMBL30377 0.74 IDO1 (0.61) IDO1MAOAMAOBNR4A2PNMT
SCHEMBL8958923 0.74 IDO1 (0.42) IDO1MAOAMAOBPNMTKMT2A
SCHEMBL991032 0.73 TSHR (0.59) IDO1MAOBRAB9ANPC1
Phosphine SCHEMBL20719631 0.72 IDO1 (0.59) IDO1MAOAMAOBNR4A2PNMT
SCHEMBL28822078 0.72 TSHR (0.57) IDO1MAOBRAB9ANPC1
SCHEMBL10336859 0.71 TSHR (0.39) KMT2AMAPTLMNAL3MBTL1
SCHEMBL31324508 0.70 IDO1 (0.50) IDO1MAOAMAOBHDAC8NR4A2
SCHEMBL9419151 0.70 IDO1 (0.52) IDO1MAOAMAOBHDAC8NR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107827706-B Method for preparing radioactive methyl iodide, radioactive methyl iodide releasing agent and method for testing radioactive gas purification capacity 广东核电合营有限公司 2021-01-26 CN disclosed
CN-107827706-A Prepare the method for testing of the method for radioactivity methyl iodide, radioactivity methyl iodide releasing agent and purifying radioactive gas ability 广东核电合营有限公司 2018-03-23 CN disclosed