Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.55 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.55 |
| ▸ | ITGAL | P20701 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CRHBP | P24387 | 2/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | OXTR | P30559 | 1/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33192 | 0.97 | — | — | |
| SCHEMBL335161 | 0.97 | — | — | |
| SCHEMBL29373453 | 0.97 | — | — | |
| SCHEMBL28287702 | 0.95 | — | — | |
| SCHEMBL9098245 | 0.95 | ITGB2 (0.55) | ITGB2ICAM1ITGALSMN1; SMN2LMNA | |
| Water SCHEMBL28018355 | 0.95 | ITGB2 (0.55) | ITGB2ICAM1ITGALSMN1; SMN2LMNA | |
| SCHEMBL30335609 | 0.95 | ITGB2 (0.55) | ITGB2ICAM1ITGALSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL11784012 | 0.93 | ITGB2 (0.52) | ITGB2ICAM1ITGALSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL11794091 | 0.93 | ITGB2 (0.52) | ITGB2ICAM1ITGALSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL11784501 | 0.93 | ITGB2 (0.52) | ITGB2ICAM1ITGALSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108047176-B | Synthesis method of dihydrobenzofuran compound with chiral quaternary carbon center | 常州合全药业有限公司 | 2021-04-20 | — | — | CN | disclosed |
| CN-108047176-A | Synthetic method with chiral quaternary carbon center Dihydrobenzofuranes compound | 常州合全药业有限公司 | 2018-05-18 | — | — | CN | disclosed |