Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 18/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.40 |
| ▸ | KDM5C | P41229 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17672418 | 0.82 | KDM5A (0.45) | KDM5AKDM5BKDM5CKDM4C | |
| Hydrochloric Acid SCHEMBL17672405 | 0.81 | KDM5A (0.44) | KDM5AKDM5BKDM5CKDM4C | |
| SCHEMBL16812287 | 0.81 | NPC1 (0.44) | KDM5AKDM5B | |
| SCHEMBL18161035 | 0.80 | KDM5A (0.44) | KDM5AKDM5BKDM5C | |
| SCHEMBL17672375 | 0.79 | KDM5A (0.57) | KDM5AKDM5BKDM5CKDM4C | |
| SCHEMBL17682468 | 0.79 | KDM5A (0.65) | KDM5AKDM5BKDM5CKDM4C | |
| SCHEMBL19514003 | 0.78 | KDM5A (0.66) | KDM5AKDM5BKDM5CKDM4C | |
| SCHEMBL28547729 | 0.78 | KDM5A (0.44) | KDM5AKDM5BKDM5CKDM4C | |
| SCHEMBL17682486 | 0.77 | KDM5A (0.67) | KDM5AKDM5BKDM5CKDM4C | |
| SCHEMBL19513972 | 0.77 | KDM5A (0.72) | KDM5AKDM5BKDM5CKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107912040-A | Pyrrolidine Amide Compounds As Histone Demethylase Inhibitors | 基因泰克公司 | 2018-04-13 | — | — | CN | disclosed |