Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 6/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31078088 | 0.84 | AAK1 (0.44) | MAPKAPK2GSK3BDYRK1AMETAP1 | |
| SCHEMBL29878128 | 0.80 | BRD9 (0.40) | BRD9MAPTCYP17A1GSK3BDYRK1A | |
| SCHEMBL5489930 | 0.80 | BRD9 (0.40) | BRD9MAPTCYP17A1GSK3BDYRK1A | |
| SCHEMBL18940478 | 0.80 | ATR (0.41) | MAPKAPK2CYP17A1GSK3BDYRK1ANAMPT | |
| SCHEMBL18961365 | 0.80 | CYP17A1 (0.38) | BRD9MAPKAPK2CYP17A1GSK3BDYRK1A | |
| SCHEMBL14822488 | 0.74 | ATR (0.40) | MAPTMAPKAPK2ATR | |
| SCHEMBL2258337 | 0.72 | MAPT (0.42) | MAPTMAPKAPK2CYP17A1NAMPTGRIN2B | |
| SCHEMBL15862073 | 0.72 | NAMPT (0.39) | MAPTMAPKAPK2DYRK1ANAMPT | |
| SCHEMBL31439890 | 0.71 | GSK3B (0.39) | BRD9MAPKAPK2CYP17A1GSK3BDYRK1A | |
| SCHEMBL3256083 | 0.71 | NPC1 (0.54) | BRD9MAPTCYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922386-A | 1,4 disubstituted imidazolium derivatives | 大日本住友制药株式会社 | 2018-04-17 | — | — | CN | disclosed |
| CN-107922348-A | Bicyclic heterocyclic amide derivatives | 大日本住友制药株式会社 | 2018-04-17 | — | — | CN | disclosed |