Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 19/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2825608 | 0.84 | DHODH (0.73) | DHODH | |
| SCHEMBL468524 | 0.80 | DHODH (1.00) | DHODH | |
| SCHEMBL468533 | 0.79 | DHODH (0.80) | DHODH | |
| SCHEMBL468552 | 0.79 | DHODH (0.80) | DHODH | |
| SCHEMBL468589 | 0.79 | DHODH (1.00) | DHODH | |
| SCHEMBL468466 | 0.79 | DHODH (1.00) | DHODH | |
| SCHEMBL468512 | 0.79 | DHODH (0.79) | DHODH | |
| SCHEMBL2825610 | 0.77 | DHODH (0.61) | DHODH | |
| SCHEMBL468440 | 0.77 | DHODH (0.81) | DHODH | |
| SCHEMBL468546 | 0.76 | DHODH (0.80) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178840-A1 | AZABIPHENYLAMINOBENZOIC ACID DERIVATIVES AS DHODH INHIBITORS | Almirall, S.A. (ES) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009021696-A1 | AZABIPHENYLAMINOBENZOIC ACID DERIVATIVES AS DHODH INHIBITORS | ALMIRALL, S.A. (ES) | 2009-02-19 | — | — | WO | disclosed |