SCHEMBL28210585

SCHEMBL28210585

Cc1ccc(CSC(=O)CCCCC(=O)O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.49
KMT2A Q03164 2/20 0.46
FFAR1 O14842 2/20 0.46
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC10 Q969S8 1/20 0.42
HDAC11 Q96DB2 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
HDAC9 Q9UKV0 1/20 0.42
HDAC5 Q9UQL6 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
TDP1 Q9NUW8 2/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MAPT P10636 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL28211211 0.97 IDO1 (0.46) IDO1KMT2AFFAR1HDAC3HDAC4
SCHEMBL28219587 0.84 MAPT (0.58) IDO1FFAR1HDAC3HDAC4HDAC1
SCHEMBL28857373 0.83 TDP1 (0.61) IDO1FFAR1HDAC3HDAC4HDAC1
SCHEMBL5180355 0.81 CYP2C19 (0.54) KMT2AFFAR1
Adipic Acid SCHEMBL3804252 0.81 KMT2A (0.61) KMT2AFFAR1HDAC11L3MBTL1TDP1
Adipic Acid SCHEMBL27731397 0.81 KMT2A (0.61) KMT2AFFAR1HDAC11L3MBTL1TDP1
Ethylene SCHEMBL28219597 0.81 MAPT (0.55) IDO1FFAR1HDAC3HDAC4HDAC1
Azelaic Acid SCHEMBL3807504 0.79 TSHR (0.60) KMT2AFFAR1HDAC11L3MBTL1TDP1
Sebacic Acid SCHEMBL36102 0.79 TSHR (0.60) KMT2AFFAR1HDAC11L3MBTL1TDP1
P-Xylene SCHEMBL36101 0.79 TSHR (0.60) KMT2AFFAR1HDAC11L3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107955823-A A kind of method of lipase-catalyzed online synthesis 6- ((4- methyl-benzyls) sulfenyl) -6- oxo vinyl caproates 浙江工业大学 2018-04-24 CN disclosed