Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.70 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.70 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 14/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Pyrrolidone SCHEMBL27573765 | 0.91 | OR51E2 (0.71) | CRBNFKBP5OR51E2KDM4EGAA | |
| Caprolactam SCHEMBL10710154 | 0.89 | CRBN (0.80) | CRBNFKBP5OR51E2KDM4EGAA | |
| Caprolactam SCHEMBL28301539 | 0.86 | CRBN (0.84) | CRBNFKBP5OR51E2KDM4EGAA | |
| Caprolactam SCHEMBL28174316 | 0.86 | CRBN (0.84) | CRBNFKBP5OR51E2KDM4EGAA | |
| SCHEMBL20885246 | 0.86 | CRBN (0.94) | CRBNFKBP5OR51E2KDM4EGAA | |
| SCHEMBL20885247 | 0.86 | CRBN (0.94) | CRBNFKBP5OR51E2KDM4EGAA | |
| SCHEMBL454341 | 0.86 | — | — | |
| SCHEMBL20589476 | 0.86 | CRBN (0.94) | CRBNFKBP5OR51E2KDM4EGAA | |
| SCHEMBL20670735 | 0.86 | CRBN (0.94) | CRBNFKBP5OR51E2KDM4EGAA | |
| SCHEMBL10586589 | 0.86 | CRBN (0.94) | CRBNFKBP5OR51E2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085565-B | A kind of preparation method of hydroxypropyl (fourth) base disiloxane | 山东大学 | 2018-05-08 | — | — | CN | claimed |