Ethylene

Ethylene

SCHEMBL28212464

C=C.CCN(CC)Cc1ccccc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.60
CNR2 P34972 1/20 0.59
KDM4E B2RXH2 1/20 0.58
TSHR P16473 3/20 0.56
MAPK1 P28482 1/20 0.56
ALDH1A1 P00352 2/20 0.52
CHRM2 P08172 1/20 0.52
HTR1A P08908 1/20 0.52
ADRA2A P08913 1/20 0.52
CHRM1 P11229 1/20 0.52
DRD1 P21728 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A4 P31645 1/20 0.52
ADRA1A P35348 1/20 0.52
OPRM1 P35372 1/20 0.52
DRD3 P35462 1/20 0.52
SLC6A3 Q01959 1/20 0.52
KCNH2 Q12809 1/20 0.52
BCHE P06276 1/20 0.51
MAOB P27338 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8064154 0.95 HRH3 (0.60) HRH3CNR2KDM4ETSHRMAPK1
SCHEMBL81248 0.95 HRH3 (0.65) HRH3CNR2KDM4ETSHRMAPK1
Hydrochloric Acid SCHEMBL890978 0.93 HRH3 (0.62) HRH3CNR2KDM4ETSHRMAPK1
Iodide SCHEMBL21693881 0.93 HRH3 (0.62) HRH3CNR2KDM4ETSHRMAPK1
Water SCHEMBL5507580 0.93 HRH3 (0.62) HRH3CNR2KDM4ETSHRMAPK1
Fluoride SCHEMBL11307410 0.93 HRH3 (0.62) HRH3CNR2KDM4ETSHRMAPK1
Bromide SCHEMBL11663269 0.93 HRH3 (0.62) HRH3CNR2KDM4ETSHRMAPK1
Chloromethane SCHEMBL27279684 0.91 HRH3 (0.60) HRH3CNR2KDM4ETSHRMAPK1
SCHEMBL375111 0.90 KDM4E (0.68) HRH3CNR2KDM4ETSHRMAPK1
Hydrochloric Acid SCHEMBL11608574 0.88 KDM4E (0.66) HRH3CNR2KDM4ETSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107920997-A Dimethyl fumarate particle and its pharmaceutical composition 比奥根MA公司 2018-04-17 CN disclosed