Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 17/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18361365 | 1.00 | HDAC1 (0.54) | HDAC1HDAC3HDAC2NCOR2MAPK1 | |
| SCHEMBL18361371 | 1.00 | HDAC1 (0.54) | HDAC1HDAC3HDAC2NCOR2MAPK1 | |
| Hydrochloric Acid SCHEMBL21043577 | 0.99 | HDAC1 (0.53) | HDAC1HDAC3HDAC2NCOR2MAPK1 | |
| Hydrochloric Acid SCHEMBL21043582 | 0.99 | HDAC1 (0.53) | HDAC1HDAC3HDAC2NCOR2MAPK1 | |
| Hydrochloric Acid SCHEMBL21043576 | 0.99 | HDAC1 (0.53) | HDAC1HDAC3HDAC2NCOR2MAPK1 | |
| SCHEMBL18361249 | 0.93 | HDAC1 (0.58) | HDAC1HDAC3HDAC2NCOR2MAPK1 | |
| SCHEMBL18361327 | 0.90 | HDAC1 (0.59) | HDAC1HDAC3HDAC2NCOR2MAPK1 | |
| Hydrochloric Acid SCHEMBL21043584 | 0.89 | HDAC1 (0.58) | HDAC1HDAC3HDAC2NCOR2MAPK1 | |
| SCHEMBL18361335 | 0.88 | HDAC1 (0.54) | HDAC1HDAC3HDAC2NCOR2MAPK1 | |
| SCHEMBL22874453 | 0.83 | HDAC1 (0.60) | HDAC1HDAC3HDAC2NCOR2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922342-A | Histone deacetylase inhibitors | 生物马林药物股份有限公司 | 2018-04-17 | — | — | CN | disclosed |