Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL742886 | 0.93 | TSHR (0.57) | TSHRHPGDHCAR2ATMALDH1A1 | |
| Vinylsulfonic Acid SCHEMBL9616554 | 0.91 | TSHR (0.46) | TSHRHPGDHCAR2ATMALDH1A1 | |
| Acrylic Acid SCHEMBL9295460 | 0.91 | TSHR (0.54) | TSHRHPGDHCAR2ATMALDH1A1 | |
| SCHEMBL375032 | 0.89 | TSHR (0.57) | TSHRHPGDHCAR2ATMALDH1A1 | |
| Acrylic Acid SCHEMBL20680727 | 0.88 | TSHR (0.53) | TSHRHPGDHCAR2ATMALDH1A1 | |
| Acrylic Acid SCHEMBL25396176 | 0.87 | TSHR (0.51) | TSHRHPGDHCAR2ATMALDH1A1 | |
| SCHEMBL10878331 | 0.87 | TSHR (0.71) | TSHRHPGDHCAR2ATMALDH1A1 | |
| Styrene SCHEMBL11607106 | 0.86 | KDM4E (0.44) | TSHRHPGDHCAR2ALDH1A1CYP3A4 | |
| Acrylic Acid SCHEMBL28301527 | 0.86 | TSHR (0.58) | TSHRHPGDHCAR2ATMALDH1A1 | |
| Acrylic Acid Ethyl Ester SCHEMBL9457892 | 0.85 | TSHR (0.64) | TSHRHPGDHCAR2ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511384-A | A kind of polyacrylate/polysilsesquioxane core-shell emulsion and preparation method thereof | UNIV BEIJING CHEM TECH | 2019-11-29 | — | — | CN | disclosed |
| CN-107903359-A | For rubber, the modified aqueous polyurethane resin and preparation method thereof of plastics | 鹤山市河本聚脂化工有限公司 | 2018-04-13 | — | — | CN | disclosed |