⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145942 | 0.81 | — | — | |
| SCHEMBL147215 | 0.74 | — | — | |
| SCHEMBL26185856 | 0.74 | — | — | |
| SCHEMBL18639790 | 0.70 | — | — | |
| SCHEMBL29015455 | 0.70 | — | — | |
| SCHEMBL25177285 | 0.70 | — | — | |
| SCHEMBL29015550 | 0.65 | POLB (0.34) | — | |
| SCHEMBL15353271 | 0.65 | HSD17B10 (0.32) | — | |
| SCHEMBL2232172 | 0.64 | — | — | |
| SCHEMBL29221526 | 0.63 | KDM1A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-107922405-A | Compound, preparation method and use with ERK kinase inhibiting activities | 中国科学院上海药物研究所 | 2018-04-17 | — | — | CN | disclosed |