Quinoline

Quinoline

SCHEMBL28215883

Nc1ccc(O)c2ncccc12.c1ccc2ncccc2c1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 4/20 0.76
IDO1 P14902 2/20 0.76
HSP90AB1 P08238 2/20 0.76
PSMB5 P28074 1/20 0.76
ALDH1A1 P00352 2/20 0.52
KDM4E B2RXH2 11/20 0.49
L3MBTL1 Q9Y468 5/20 0.49
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
NPSR1 Q6W5P4 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
LMNA P02545 2/20 0.49
HTT P42858 2/20 0.49
METAP2 P50579 2/20 0.49
METAP1 P53582 2/20 0.49
MAPT P10636 2/20 0.49
MPI P34949 1/20 0.49
BRD4 O60885 1/20 0.49
SLC6A2 P23975 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29721839 0.87 HSP90AA1 (1.00) HSP90AA1IDO1HSP90AB1PSMB5ALDH1A1
SCHEMBL688655 0.87 HSP90AA1 (1.00) HSP90AA1IDO1HSP90AB1PSMB5ALDH1A1
SCHEMBL31441084 0.85 HSP90AA1 (0.96) HSP90AA1IDO1HSP90AB1PSMB5ALDH1A1
Hydrochloric Acid SCHEMBL4457813 0.85 HSP90AA1 (0.96) HSP90AA1IDO1HSP90AB1PSMB5ALDH1A1
SCHEMBL31441082 0.85 HSP90AA1 (0.96) HSP90AA1IDO1HSP90AB1PSMB5ALDH1A1
Hydrochloric Acid SCHEMBL29845219 0.85 HSP90AA1 (0.96) HSP90AA1IDO1HSP90AB1PSMB5ALDH1A1
Bromide SCHEMBL7118628 0.85 HSP90AA1 (0.96) HSP90AA1IDO1HSP90AB1PSMB5ALDH1A1
Hydrochloric Acid SCHEMBL361071 0.85 HSP90AA1 (0.96) HSP90AA1IDO1HSP90AB1PSMB5ALDH1A1
Hydrochloric Acid SCHEMBL3682081 0.85 HSP90AA1 (0.96) HSP90AA1IDO1HSP90AB1PSMB5ALDH1A1
Hydrochloric Acid SCHEMBL27468026 0.85 HSP90AA1 (0.96) HSP90AA1IDO1HSP90AB1PSMB5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108027557-B Cured film and its manufacturing method 东丽株式会社 2019-05-28 CN disclosed
CN-108473679-A Cured film and its manufacturing method 东丽株式会社 2018-08-31 CN disclosed
CN-108027557-A Cured film and its manufacture method 东丽株式会社 2018-05-11 CN disclosed