Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 5/20 | 0.35 |
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571410 | 0.78 | TDP1 (0.46) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL10323475 | 0.75 | MEN1 (0.45) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL10323476 | 0.75 | MEN1 (0.45) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL1827298 | 0.74 | MEN1 (0.47) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL27900273 | 0.73 | MEN1 (0.38) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL842921 | 0.73 | TDP1 (0.52) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL21065336 | 0.73 | TDP1 (0.52) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL255203 | 0.73 | TDP1 (0.52) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL6599853 | 0.73 | MEN1 (0.35) | MEN1KMT2AGAATDP1CTSK | |
| SCHEMBL6599858 | 0.73 | MEN1 (0.35) | MEN1KMT2AGAATDP1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026026-A | Beta-amino acids and analog and its application as the β-substituted of chemotherapeutics | 夸德里加生物科学公司 | 2018-05-11 | — | — | CN | disclosed |