Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.60 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.55 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | SHBG | P04278 | 2/20 | 0.50 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.50 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542864 | 0.82 | CYP19A1 (0.64) | CYP19A1AKR1B10AKR1B1OR51E2MEN1 | |
| SCHEMBL8542867 | 0.82 | CYP19A1 (0.64) | CYP19A1AKR1B10AKR1B1OR51E2MEN1 | |
| SCHEMBL3649455 | 0.82 | CYP19A1 (0.58) | CYP19A1AKR1B10AKR1B1OR51E2 | |
| SCHEMBL3649456 | 0.82 | CYP19A1 (0.58) | CYP19A1AKR1B10AKR1B1OR51E2 | |
| SCHEMBL3660084 | 0.82 | CYP19A1 (0.57) | CYP19A1OR51E2GPBAR1LMNACYP3A4 | |
| SCHEMBL3660082 | 0.82 | CYP19A1 (0.57) | CYP19A1OR51E2GPBAR1LMNACYP3A4 | |
| SCHEMBL9471786 | 0.81 | CYP19A1 (0.63) | CYP19A1AKR1B10AKR1B1OR51E2MEN1 | |
| SCHEMBL3656561 | 0.81 | CYP19A1 (0.63) | CYP19A1AKR1B10AKR1B1OR51E2MEN1 | |
| SCHEMBL9471777 | 0.81 | CYP19A1 (0.63) | CYP19A1AKR1B10AKR1B1OR51E2MEN1 | |
| SCHEMBL4931829 | 0.81 | CYP19A1 (0.63) | CYP19A1AKR1B10AKR1B1OR51E2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104710495-B | A kind of preparation method of pregnant steroid -16- alkene -3,20- diketone steroid derivative | 天津金耀集团有限公司 | 2018-06-05 | — | — | CN | disclosed |