Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.96 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10586702 | 0.98 | TSHR (1.00) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL1977194 | 0.98 | TSHR (1.00) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL33994 | 0.98 | TSHR (1.00) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL21853811 | 0.98 | TSHR (1.00) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL21853806 | 0.98 | TSHR (1.00) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL6655183 | 0.98 | TSHR (1.00) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL11775454 | 0.98 | TSHR (1.00) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL15200 | 0.98 | TSHR (1.00) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL14995 | 0.98 | TSHR (1.00) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL22579031 | 0.98 | TSHR (1.00) | TSHRTHRBNAAAPOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109004269-A | Preparation method of self-assembled polyimidazole type all-solid-state polymer electrolyte containing 2D channel | 南昌航空大学 | 2018-12-14 | — | — | CN | claimed |
| CN-109004269-A | Preparation method of self-assembled polyimidazole type all-solid-state polymer electrolyte containing 2D channel | 南昌航空大学 | 2018-12-14 | — | — | CN | disclosed |
| CN-107946641-A | Ion liquid crystal/polyimidazole semi-interpenetrating network polymer electrolyte preparation method | 南昌航空大学 | 2018-04-20 | — | — | CN | disclosed |