Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 8/20 | 0.41 |
| ▸ | BCHE | P06276 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623297 | 0.91 | NPY5R (0.51) | NPY5RRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL28825806 | 0.85 | NPY5R (0.48) | NPY5RRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL5370760 | 0.80 | NPY5R (0.57) | NPY5RRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL11073998 | 0.79 | ATM (0.50) | NPY5RRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL5804088 | 0.78 | NPY5R (0.49) | NPY5RRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL3475218 | 0.75 | NPY5R (0.59) | NPY5RRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL28050440 | 0.75 | NPY5R (0.52) | NPY5RRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL28050443 | 0.75 | NPY5R (0.52) | NPY5RRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL28050399 | 0.75 | NPY5R (0.52) | NPY5RRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL4924150 | 0.74 | NPY5R (0.51) | NPY5RRAB9AALDH1A1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108434149-A | For the regulated treatments of HSPC of Rb positive abnormal cell proliferations | G1治疗公司 | 2018-08-24 | — | — | CN | disclosed |
| CN-105407889-B | HSPC-sparing therapy for Rb-positive abnormal cell proliferation | G1治疗公司 | 2018-06-01 | — | — | CN | disclosed |