Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2821724 | 1.00 | KCNH2 (0.43) | KCNH2SLC2A1 | |
| SCHEMBL3602618 | 0.81 | CYP2D6 (0.41) | KCNH2SLC2A1 | |
| SCHEMBL3551285 | 0.77 | KCNH2 (0.39) | KCNH2SLC2A1 | |
| SCHEMBL909966 | 0.77 | KCNH2 (0.45) | KCNH2SLC2A1 | |
| SCHEMBL910385 | 0.77 | KCNH2 (0.45) | KCNH2SLC2A1 | |
| SCHEMBL909967 | 0.77 | KCNH2 (0.45) | KCNH2SLC2A1 | |
| SCHEMBL2502423 | 0.76 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL3217443 | 0.75 | SLC2A1 (0.35) | KCNH2SLC2A1 | |
| SCHEMBL910445 | 0.74 | KCNH2 (0.39) | KCNH2 | |
| SCHEMBL910443 | 0.74 | KCNH2 (0.39) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041145-B1 | AZATRICYCLIC COMPOUNDS AND THEIR USE | GLAXO GROUP LTD (GB) | 2010-10-27 | — | — | EP | disclosed |