SCHEMBL28218239

SCHEMBL28218239

NC(=S)C1CC=NO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20789205 0.59
SCHEMBL28108454 0.59
SCHEMBL467970 0.47
Thiourea SCHEMBL850383 0.43
Thiourea SCHEMBL1008 0.43
Dioxane SCHEMBL22721823 0.43 TSHR (0.50)
Adamantane SCHEMBL25171693 0.43 TSHR (0.50)
Hydrazine SCHEMBL3798832 0.43
SCHEMBL14675637 0.43 TSHR (0.50)
SCHEMBL23813060 0.43

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104797564-B The 3- phenyl-isoxazole oxazoline -5- thioamides of the 3- phenyl-isoxazoles oxazoline -5- formamides and 5- epoxides of weeding and antifungal 5- epoxides-substituted-substituted 拜尔农作物科学股份公司 2018-05-04 CN claimed
CN-104797577-B Weeding and the formamide of 3 heteroaryl isoxazoline 5 and the thioamides of 3 heteroaryl isoxazoline 5 of Fungicidally active 拜尔农作物科学股份公司 2018-01-12 CN claimed
CN-104797577-A Herbicidally and fungicidally active 3-heteroaryl-isoxazoline-5-carboxamides and 3-heteroaryl-isoxazoline-5-thioamides BAYER CROPSCIENCE AG 2015-07-22 CN claimed
CN-111164077-B Herbicidal 3-phenyl-5-trifluoromethyl isoxazoline-5-carboxamides of cyclopentylcarboxylic acids and esters thereof 拜耳公司 2023-12-19 CN disclosed
CN-111868042-B Herbicidal 3-phenylisoxazoline-5-carboxamides of cyclopentylcarboxylic acid derivatives 拜耳公司 2023-12-05 CN disclosed
CN-110799511-B Herbicidal 3-phenylisoxazoline-5-carboxamides of tetrahydro-and dihydrofurancarboxamides 拜耳公司 2023-09-01 CN disclosed
CN-110770232-B Herbicidal 3-phenylisoxazoline-5-carboxamides of tetrahydro-and dihydrofuran carboxylic acids and esters 拜耳公司 2023-08-15 CN disclosed
CN-111868042-A Herbicidally active 3-phenylisoxazoline-5-carboxamides of cyclopentyl carboxylic acid derivatives 拜耳公司 2020-10-30 CN disclosed
CN-111164077-A Herbicidally active 3-phenyl-5-trifluoromethyl-isoxazoline-5-carboxamides of cyclopentylcarboxylic acids and esters thereof 拜耳公司 2020-05-15 CN disclosed
CN-110799511-A Herbicidally active 3-phenylisoxazoline-5-carboxamides of tetrahydro-and dihydrofurancarboxamides 拜耳公司 2020-02-14 CN disclosed
CN-110770232-A Herbicidally active 3-phenylisoxazoline-5-carboxamides of tetrahydro-and dihydrofurancarboxylic acids and esters 拜耳公司 2020-02-07 CN disclosed
CN-104797564-B The 3- phenyl-isoxazole oxazoline -5- thioamides of the 3- phenyl-isoxazoles oxazoline -5- formamides and 5- epoxides of weeding and antifungal 5- epoxides-substituted-substituted 拜尔农作物科学股份公司 2018-05-04 CN disclosed
CN-104797577-B Weeding and the formamide of 3 heteroaryl isoxazoline 5 and the thioamides of 3 heteroaryl isoxazoline 5 of Fungicidally active 拜尔农作物科学股份公司 2018-01-12 CN disclosed
CN-104797577-A Herbicidally and fungicidally active 3-heteroaryl-isoxazoline-5-carboxamides and 3-heteroaryl-isoxazoline-5-thioamides BAYER CROPSCIENCE AG 2015-07-22 CN disclosed