Cyclopropane

Cyclopropane

SCHEMBL28218385

C1CC1.NC(N)(c1ccccc1)c1ccccc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.58
CYP2B6 P20813 1/20 0.44
TSHR P16473 2/20 0.43
ALDH1A1 P00352 1/20 0.43
TAAR1 Q96RJ0 1/20 0.40
PTPN1 P18031 1/20 0.39
CYP2D6 P10635 2/20 0.38
CYP1A2 P05177 1/20 0.38
MAPK1 P28482 1/20 0.38
LMNA P02545 1/20 0.38
CHRM2 P08172 1/20 0.38
HTR1A P08908 1/20 0.38
CHRM1 P11229 1/20 0.38
OPRM1 P35372 1/20 0.38
KCNH2 Q12809 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15366 0.90 KCNN4 (0.69) KCNN4TSHRALDH1A1TAAR1PTPN1
Hydrochloric Acid SCHEMBL1165109 0.87 KCNN4 (0.65) KCNN4TSHRALDH1A1TAAR1PTPN1
Ammonia Solution, Strong SCHEMBL8652805 0.87 KCNN4 (0.65) KCNN4TSHRALDH1A1TAAR1PTPN1
Methane SCHEMBL20815707 0.87 KCNN4 (0.65) KCNN4TSHRALDH1A1TAAR1PTPN1
SCHEMBL28861251 0.87 KCNN4 (0.65) KCNN4TSHRALDH1A1TAAR1PTPN1
Ammonia Solution, Strong SCHEMBL4651889 0.87 KCNN4 (0.65) KCNN4TSHRALDH1A1TAAR1PTPN1
Hydrochloric Acid SCHEMBL11425222 0.87 KCNN4 (0.65) KCNN4TSHRALDH1A1TAAR1PTPN1
Lithium SCHEMBL29464023 0.84 KCNN4 (0.61) KCNN4TSHRALDH1A1TAAR1PTPN1
Hydrochloric Acid SCHEMBL28486217 0.84 KCNN4 (0.61) KCNN4TSHRALDH1A1TAAR1PTPN1
Cyclohexylamine SCHEMBL28823963 0.83 CHRM2 (0.44) KCNN4CYP2B6TSHRCYP2D6CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103657011-B Golf composition 阿库施耐特公司 2018-05-01 CN disclosed