Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.72 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.62 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.57 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | TCF4 | P15884 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15761753 | 0.88 | HIF1A (0.85) | HIF1ACA1CA2SENP1LOXL2 | |
| SCHEMBL15761744 | 0.87 | HIF1A (0.67) | HIF1ACA1CA2SENP1LOXL2 | |
| SCHEMBL15755382 | 0.87 | HIF1A (0.70) | HIF1ACA1CA2SENP1LOXL2 | |
| SCHEMBL15761718 | 0.87 | HIF1A (0.70) | HIF1ACA1CA2SENP1LOXL2 | |
| SCHEMBL16550428 | 0.85 | HIF1A (0.70) | HIF1AHTTHDAC8HDAC6FFAR1 | |
| SCHEMBL18300943 | 0.83 | HIF1A (0.61) | HIF1ACA1CA2SENP1LOXL2 | |
| SCHEMBL17618029 | 0.82 | CA1 (0.77) | CA1CA2LOXL2MAPTPOLB | |
| SCHEMBL15761745 | 0.81 | HIF1A (0.65) | HIF1ACA1CA2SENP1LOXL2 | |
| SCHEMBL15761730 | 0.81 | HIF1A (0.65) | HIF1ACA1CA2SENP1LOXL2 | |
| SCHEMBL15761741 | 0.81 | HIF1A (0.65) | HIF1ACA1CA2SENP1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137518-A | As 6 inhibitor of histone deacetylase 1,3,4- oxadiazole derivatives compound and include its pharmaceutical composition | 株式会社钟根堂 | 2018-06-08 | — | — | CN | disclosed |