Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.49 |
| ▸ | SORD | Q00796 | 4/20 | 0.48 |
| ▸ | OGA | O60502 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3949154 | 0.85 | TRPV1 (0.51) | TRPV1SORDOGAHRH3HRH4 | |
| SCHEMBL29519276 | 0.85 | TRPV1 (0.51) | TRPV1SORDOGAHRH3HRH4 | |
| SCHEMBL1427479 | 0.85 | TRPV1 (0.51) | TRPV1SORDOGAHRH3HRH4 | |
| SCHEMBL2087838 | 0.83 | CXCR4 (0.51) | TRPV1SORDOGAHRH3HRH4 | |
| SCHEMBL1088796 | 0.83 | CXCR4 (0.51) | TRPV1SORDOGAHRH3HRH4 | |
| SCHEMBL20361965 | 0.81 | TRPV1 (0.49) | TRPV1SORDOGAHRH3HRH4 | |
| SCHEMBL11823109 | 0.80 | TRPV1 (0.48) | TRPV1SORDOGAHRH3HRH4 | |
| SCHEMBL2190955 | 0.80 | HRH4 (0.65) | TRPV1SORDHRH3HRH4 | |
| SCHEMBL1110658 | 0.80 | PIK3CA (0.50) | TRPV1SORDOGA | |
| SCHEMBL29997962 | 0.80 | HRH4 (0.65) | TRPV1SORDHRH3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108135175-B | Bicyclic compounds and their use for inhibition of SUV39H2 | 肿瘤疗法科学股份有限公司 | 2021-04-06 | — | — | CN | disclosed |
| CN-108135175-A | Bicyclic compounds and their use for inhibition of SUV39H2 | 肿瘤疗法科学股份有限公司 | 2018-06-08 | — | — | CN | disclosed |