Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 3/20 | 0.49 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28219941 | 0.98 | MAP3K5 (0.50) | MAP3K5FDPSLTA4HGAAHDAC3 | |
| SCHEMBL28347289 | 0.86 | MAP3K5 (0.50) | MAP3K5FDPSGAASMN1; SMN2MAPT | |
| SCHEMBL28357831 | 0.84 | CCNK (0.53) | MAP3K5FDPSGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL28340206 | 0.82 | MAP3K5 (0.51) | MAP3K5FDPSHDAC3HDAC4HDAC1 | |
| SCHEMBL28224833 | 0.82 | ADORA1 (0.52) | MAP3K5FDPSGAAMAPTALDH1A1 | |
| SCHEMBL8986816 | 0.80 | MAP3K5 (0.54) | MAP3K5FDPSGAAMAPTALDH1A1 | |
| SCHEMBL31143762 | 0.80 | MAP3K5 (0.54) | MAP3K5FDPSGAAMAPTALDH1A1 | |
| SCHEMBL31060745 | 0.79 | NPC1 (0.58) | MAP3K5FDPSGAASMN1; SMN2MAPT | |
| SCHEMBL6307534 | 0.79 | NPC1 (0.58) | MAP3K5FDPSGAASMN1; SMN2MAPT | |
| SCHEMBL1483456 | 0.79 | MAP3K5 (0.68) | MAP3K5FDPSSMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108125959-A | Dimethoxy benzene aminoacetylamino quinazoline compounds are preparing the application in treating leukemia medicament | 浙江工业大学 | 2018-06-08 | — | — | CN | claimed |
| CN-108125959-A | Dimethoxy benzene aminoacetylamino quinazoline compounds are preparing the application in treating leukemia medicament | 浙江工业大学 | 2018-06-08 | — | — | CN | disclosed |
| CN-108125959-A | Dimethoxy benzene aminoacetylamino quinazoline compounds are preparing the application in treating leukemia medicament | 浙江工业大学 | 2018-06-08 | — | — | CN | disclosed |
| CN-108125959-A | Dimethoxy benzene aminoacetylamino quinazoline compounds are preparing the application in treating leukemia medicament | 浙江工业大学 | 2018-06-08 | — | — | CN | disclosed |