Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 9/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2828867 | 0.90 | PPARD (0.44) | PPARDPPARAMAOBPPARGMRGPRX4 | |
| SCHEMBL2822203 | 0.86 | PPARD (0.47) | PPARDPPARAMAOBPPARGMRGPRX4 | |
| SCHEMBL2823026 | 0.84 | PPARD (0.44) | PPARDMAOBMRGPRX4MAOAAR | |
| SCHEMBL2069836 | 0.82 | PPARD (0.73) | PPARDPPARAPPARG | |
| SCHEMBL2068513 | 0.79 | PPARD (0.53) | PPARDPPARAMRGPRX4 | |
| SCHEMBL2068871 | 0.74 | PPARD (0.68) | PPARDPPARAPPARG | |
| SCHEMBL3960058 | 0.72 | PPARD (0.67) | PPARDPPARAPPARG | |
| SCHEMBL2823029 | 0.69 | MAOB (0.46) | PPARDMAOBMRGPRX4MAOA | |
| SCHEMBL3028480 | 0.67 | PDE2A (0.42) | — | |
| SCHEMBL14437998 | 0.67 | MAOB (0.70) | MAOBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745003-B1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-10-27 | — | — | EP | claimed |