Chloroform

Chloroform

SCHEMBL28222011

CSCC(N)C(=O)O.ClC(Cl)Cl

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.44
ARG1 P05089 1/20 0.44
ARG2 P78540 1/20 0.44
NOS2 P35228 4/20 0.43
NOS1 P29475 3/20 0.43
NOS3 P29474 2/20 0.43
PTGS1 P23219 1/20 0.42
SLC7A11 Q9UPY5 1/20 0.42
KIF11 P52732 5/20 0.42
SLC1A3 P43003 3/20 0.40
SLC1A2 P43004 3/20 0.40
SLC1A1 P43005 3/20 0.40
ALDH1A1 P00352 1/20 0.40
ALOX15 P16050 1/20 0.40
RNPEP Q9H4A4 1/20 0.40
GRIK1 P39086 2/20 0.39
GRM8 O00222 1/20 0.39
GRM6 O15303 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4992004 0.93
SCHEMBL110459 0.93
SCHEMBL110458 0.93
Hydrochloric Acid SCHEMBL202708 0.90
SCHEMBL21489523 0.90 SLC7A5 (0.48) SLC7A5ARG1ARG2NOS2NOS1
Hydrochloric Acid SCHEMBL7756974 0.90
Hydrochloric Acid SCHEMBL28195056 0.90
SCHEMBL11582175 0.88 PTGS1 (0.50) SLC7A5ARG1ARG2NOS2NOS1
Glycine SCHEMBL28312688 0.84 GLRA1 (0.46) SLC7A5ARG1ARG2NOS2NOS1
Cysteine SCHEMBL8936195 0.82 PTGS1 (0.70) SLC7A5ARG1ARG2NOS2NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108192069-A A kind of selfreparing hydrogel based on double selenium dynamic covalent bonds and Quadrupolar hydrogen bond 四川大学 2018-06-22 CN claimed