Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 11/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MPL | P40238 | 2/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7043888 | 0.70 | MKNK1 (0.48) | MKNK1KDRMKNK2MPLGSK3A | |
| SCHEMBL147860 | 0.68 | MKNK1 (0.44) | MKNK1KDRMKNK2MPLGSK3A | |
| SCHEMBL14843891 | 0.67 | MKNK1 (0.49) | MKNK1KDRMKNK2MPLGSK3A | |
| SCHEMBL4400350 | 0.66 | EGFR (0.54) | MKNK1MKNK2HTTSMN1; SMN2EGFR | |
| SCHEMBL30199845 | 0.66 | EGFR (0.54) | MKNK1MKNK2HTTSMN1; SMN2EGFR | |
| SCHEMBL4630887 | 0.66 | GSK3A (0.53) | MKNK1KDRMKNK2HTTGSK3A | |
| SCHEMBL28618764 | 0.66 | ABCG2 (0.54) | MKNK1KDREGFR | |
| SCHEMBL31235691 | 0.66 | ABCG2 (0.54) | MKNK1KDREGFR | |
| SCHEMBL18786607 | 0.66 | MKNK1 (0.56) | MKNK1KDRMKNK2MPL | |
| SCHEMBL29941689 | 0.65 | LCK (0.49) | MKNK1KDRMKNK2MPLGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108210469-A | Freeze-dried drug nano suspension | 詹森药业有限公司 | 2018-06-29 | — | — | CN | disclosed |