Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.56 |
| ▸ | AGXT | P21549 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.49 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | LPO | P22079 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29624521 | 1.00 | IDO1 (0.56) | IDO1AGXTTAAR1CHRM2CHRM1 | |
| SCHEMBL28743543 | 1.00 | IDO1 (0.56) | IDO1AGXTTAAR1CHRM2CHRM1 | |
| SCHEMBL28230126 | 0.85 | TAAR1 (0.55) | IDO1AGXTTAAR1CHRM2CHRM1 | |
| SCHEMBL6158441 | 0.82 | IDO1 (0.56) | IDO1AGXTTAAR1CHRM2CHRM1 | |
| SCHEMBL27610564 | 0.82 | IDO1 (0.56) | IDO1AGXTTAAR1CHRM2CHRM1 | |
| SCHEMBL28084246 | 0.82 | IDO1 (0.56) | IDO1AGXTTAAR1CHRM2CHRM1 | |
| SCHEMBL8305017 | 0.81 | TAAR1 (0.58) | IDO1AGXTTAAR1CHRM2CHRM1 | |
| SCHEMBL3503547 | 0.79 | TAAR1 (0.56) | IDO1AGXTTAAR1CHRM2CHRM1 | |
| SCHEMBL248658 | 0.79 | CHRM2 (0.57) | IDO1AGXTTAAR1CHRM2CHRM1 | |
| SCHEMBL27510211 | 0.79 | IDO1 (0.53) | IDO1AGXTTAAR1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108101826-B | Indole-substituted alkylamine compound and application thereof | 华东理工大学 | 2022-05-10 | — | — | CN | disclosed |
| CN-108101826-A | Indoles substituted alkylamine class compound and application thereof | 华东理工大学 | 2018-06-01 | — | — | CN | disclosed |