SCHEMBL28224734

SCHEMBL28224734

CC(C)NNC=O.O=C1CNC(=O)N1c1cc(Cl)cc(Cl)c1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.36
USP2 O75604 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.34
CCNA2 P20248 1/20 0.33
CDK2 P24941 1/20 0.33
CCNA1 P78396 1/20 0.33
BCL2A1 Q16548 1/20 0.32
PHGDH O43175 1/20 0.32
XIAP P98170 1/20 0.32
BIRC2 Q13490 1/20 0.32
TP53 P04637 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
ADRB1 P08588 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3841672 0.80 AR (0.50) ARUSP2ALDH1A1TSHRBCL2A1
Formamide SCHEMBL28224738 0.78 AR (0.44) ARUSP2ALDH1A1TSHRBCL2A1
SCHEMBL28852120 0.73 AR (0.38) ARUSP2ALDH1A1TSHRCCNA2
SCHEMBL28180535 0.72 AR (0.44) ARUSP2ALDH1A1TSHRBCL2A1
SCHEMBL28181223 0.70 SMN1; SMN2 (0.41) ARUSP2ALDH1A1TSHRCCNA2
SCHEMBL28225425 0.67 USP2 (0.40) ARUSP2ALDH1A1TSHRCCNA2
SCHEMBL3838102 0.66 GAA (0.53) ARALDH1A1TSHRSMN1; SMN2CHRM2
SCHEMBL11076904 0.64 KMT2A (0.61) ARALDH1A1TSHRBCL2A1TP53
SCHEMBL11662447 0.64 AR (0.49) ARALDH1A1
SCHEMBL1553420 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105777647-B A kind of method for synthesizing 1- isopropylamino formamides -3- (3,5- dichlorophenyls) hydantoins 江苏快达农化股份有限公司 2018-06-01 CN claimed
CN-105777647-B A kind of method for synthesizing 1- isopropylamino formamides -3- (3,5- dichlorophenyls) hydantoins 江苏快达农化股份有限公司 2018-06-01 CN disclosed
CN-105777647-B A kind of method for synthesizing 1- isopropylamino formamides -3- (3,5- dichlorophenyls) hydantoins 江苏快达农化股份有限公司 2018-06-01 CN disclosed