Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28376945 | 0.86 | SMN1; SMN2 (0.74) | SMN1; SMN2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL28871785 | 0.80 | TLR7 (0.56) | KDM5ASMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL28235327 | 0.80 | KDM5A (0.56) | KDM5ASMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL28871761 | 0.79 | TLR7 (0.57) | KDM5ASMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL28871743 | 0.79 | GAA (0.59) | KDM5ASMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL28871823 | 0.79 | NPC1 (0.64) | KDM5ASMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL1147702 | 0.77 | KDM4E (0.73) | KDM5ASMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL10062372 | 0.77 | KDM5A (1.00) | KDM5ASMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL6634130 | 0.76 | NPC1 (0.70) | SMN1; SMN2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL28862228 | 0.76 | KDM5A (0.51) | KDM5ASMN1; SMN2ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108314644-A | A kind of synthetic method of naphthylamine derivative | 浙江工业大学 | 2018-07-24 | — | — | CN | disclosed |
| CN-108250135-A | A kind of preparation method of naphthylamine derivative | 浙江工业大学 | 2018-07-06 | — | — | CN | disclosed |