Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | CPT2 | P23786 | 1/20 | 0.58 |
| ▸ | CPT1A | P50416 | 1/20 | 0.58 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.51 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.51 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.51 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.51 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27180679 | 0.85 | MEN1 (0.75) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL30926769 | 0.85 | MEN1 (0.75) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL2823097 | 0.85 | CPT2 (0.60) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL2828714 | 0.80 | MEN1 (0.74) | MEN1KMT2AMAPTLMNACPT2 | |
| SCHEMBL30926624 | 0.79 | MEN1 (0.81) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL27180183 | 0.79 | MEN1 (0.81) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL27179665 | 0.77 | MAPT (0.70) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL30927067 | 0.77 | MAPT (0.70) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL30926902 | 0.76 | MEN1 (0.59) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL27180384 | 0.76 | MEN1 (0.59) | MEN1KMT2AMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891001-B1 | SULFONAMIDE DERIVATIVES USEFUL AS LIVER CARNITINE PALMITOYL TRANSFERASE (L-CPTl) INHIBITORS | HOFFMANN LA ROCHE (CH) | 2010-05-05 | — | — | EP | claimed |