Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.73 |
| ▸ | MAOA | P21397 | 1/20 | 0.73 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.64 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.64 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991408 | 0.86 | MAOB (0.79) | MAOBMAOACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL28317001 | 0.84 | MAOB (0.79) | MAOBMAOACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL17554366 | 0.83 | MAOB (0.73) | MAOBMAOACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL4456929 | 0.81 | GSK3B (0.59) | MAOBMAOAALDH1A1MEN1LMNA | |
| SCHEMBL17560021 | 0.80 | MAOB (0.70) | MAOBMAOACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6599866 | 0.80 | MAOB (0.68) | MAOBMAOAMAPTALDH1A1RAB9A | |
| SCHEMBL3499926 | 0.80 | MAOB (0.69) | MAOBMAOACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL28979209 | 0.79 | PARP10 (0.56) | MAOBMAOAALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL12010999 | 0.79 | MAOB (0.67) | MAOBMAOACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL27863133 | 0.79 | MAOB (0.67) | MAOBMAOACYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115873909-B | Preparation method of arformoterol chiral intermediate | 天津法莫西生物医药科技有限公司 | 2023-08-11 | — | — | CN | claimed |
| CN-115873909-A | Preparation method of arformoterol chiral intermediate | 天津法莫西生物医药科技有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-112279776-B | Method for synthesizing arformoterol free alkali | 扬州中宝药业股份有限公司 | 2022-09-02 | — | — | CN | claimed |
| CN-108358791-A | A kind of preparation method of 3- nitros -4- benzyloxy -2- bromoacetophenones | 南京法恩化学有限公司 | 2018-08-03 | — | — | CN | claimed |
| CN-115873909-B | Preparation method of arformoterol chiral intermediate | 天津法莫西生物医药科技有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-115873909-B | Preparation method of arformoterol chiral intermediate | 天津法莫西生物医药科技有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-115873909-A | Preparation method of arformoterol chiral intermediate | 天津法莫西生物医药科技有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-115873909-A | Preparation method of arformoterol chiral intermediate | 天津法莫西生物医药科技有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-112279776-B | Method for synthesizing arformoterol free alkali | 扬州中宝药业股份有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-111944855-B | Method for synthesizing (R) -1- (4- (benzyloxy) -3-nitrophenyl) -2-bromoethanol | 扬州中宝药业股份有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-112279776-A | Method for synthesizing arformoterol free alkali | 扬州中宝药业股份有限公司 | 2021-01-29 | — | — | CN | disclosed |
| CN-108358791-A | A kind of preparation method of 3- nitros -4- benzyloxy -2- bromoacetophenones | 南京法恩化学有限公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-108358791-A | A kind of preparation method of 3- nitros -4- benzyloxy -2- bromoacetophenones | 南京法恩化学有限公司 | 2018-08-03 | — | — | CN | disclosed |