Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triacetin SCHEMBL9456160 | 0.98 | TDP1 (0.46) | TDP1ARGAAPRKCASMN1; SMN2 | |
| Triacetin SCHEMBL821340 | 0.89 | TDP1 (0.56) | TDP1ARGAAPRKCASMN1; SMN2 | |
| Triacetin SCHEMBL3870 | 0.89 | TDP1 (0.56) | TDP1ARGAAPRKCASMN1; SMN2 | |
| Triacetin SCHEMBL31301065 | 0.87 | TDP1 (0.54) | TDP1ARGAAPRKCASMN1; SMN2 | |
| Triacetin SCHEMBL4367394 | 0.87 | TDP1 (0.54) | TDP1ARGAAPRKCASMN1; SMN2 | |
| Triacetin SCHEMBL30661717 | 0.87 | TDP1 (0.54) | TDP1ARGAAPRKCASMN1; SMN2 | |
| Triacetin SCHEMBL16446056 | 0.87 | TDP1 (0.54) | TDP1ARGAAPRKCASMN1; SMN2 | |
| Triacetin SCHEMBL16445622 | 0.87 | TDP1 (0.54) | TDP1ARGAAPRKCASMN1; SMN2 | |
| Triacetin SCHEMBL31035933 | 0.87 | TDP1 (0.54) | TDP1ARGAAPRKCASMN1; SMN2 | |
| Triacetin SCHEMBL8012678 | 0.87 | TDP1 (0.54) | TDP1ARGAAPRKCASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104168896-B | The fixed dosage combination treatment of Parkinson's disease | 图必制药公司 | 2018-08-10 | — | — | CN | disclosed |