Biphenyl

Biphenyl

SCHEMBL28236205

c1ccc(-c2cccc3cc4c(-c5ccccc5)cccc4cc23)cc1.c1ccc(-c2ccccc2)cc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNF P01375 1/20 0.52
ALDH1A1 P00352 8/20 0.50
HPGD P15428 4/20 0.50
KDM4E B2RXH2 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
MAPT P10636 1/20 0.50
MPI P34949 1/20 0.50
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA9 Q16790 2/20 0.46
HSD17B1 P14061 1/20 0.46
HSD17B2 P37059 1/20 0.46
HSD17B10 Q99714 5/20 0.43
HIF1A Q16665 3/20 0.43
MAPK1 P28482 3/20 0.43
TSHR P16473 2/20 0.43
CASP1 P29466 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL20533557 1.00 TNF (0.52) TNFALDH1A1HPGDKDM4EMEN1
SCHEMBL4331306 0.98 TNF (0.53) TNFALDH1A1HPGDKDM4EMEN1
SCHEMBL30645491 0.98 TNF (0.53) TNFALDH1A1HPGDKDM4EMEN1
Biphenyl SCHEMBL27655664 0.96 TNF (0.48) TNFALDH1A1HPGDKDM4EMEN1
Biphenyl SCHEMBL27587049 0.94 TNF (0.47) TNFALDH1A1HPGDKDM4EMEN1
SCHEMBL5713441 0.94 TNF (0.47) TNFALDH1A1HPGDKDM4EMEN1
SCHEMBL60347 0.93 TNF (0.50) TNFALDH1A1HPGDKDM4EMEN1
SCHEMBL30332794 0.93 TNF (0.50) TNFALDH1A1HPGDKDM4EMEN1
SCHEMBL17443013 0.92 TNF (0.46) TNFALDH1A1HPGDKDM4EMEN1
SCHEMBL23327305 0.91 TNF (0.48) TNFALDH1A1HPGDKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106058066-B Organic electroluminescence device and preparation method thereof, display device 京东方科技集团股份有限公司 2018-09-07 CN claimed