Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 10/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28236294 | 1.00 | HDAC8 (0.44) | HDAC8MEN1KMT2ASIRT5CA2 | |
| SCHEMBL18921022 | 0.92 | MEN1 (0.44) | HDAC8MEN1KMT2ACA2CTSS | |
| SCHEMBL18921021 | 0.92 | MEN1 (0.44) | HDAC8MEN1KMT2ACA2CTSS | |
| SCHEMBL17595568 | 0.86 | MEN1 (0.41) | HDAC8MEN1KMT2ASIRT5CA2 | |
| SCHEMBL17595565 | 0.86 | MEN1 (0.41) | HDAC8MEN1KMT2ASIRT5CA2 | |
| SCHEMBL29127370 | 0.85 | HDAC8 (0.43) | HDAC8MEN1KMT2ASIRT5CA2 | |
| SCHEMBL19302582 | 0.84 | MEN1 (0.55) | MEN1KMT2ACA2CTSSCTSK | |
| SCHEMBL17595996 | 0.83 | MEN1 (0.45) | HDAC8MEN1KMT2ACA2CTSS | |
| SCHEMBL17595993 | 0.83 | MEN1 (0.45) | HDAC8MEN1KMT2ACA2CTSS | |
| SCHEMBL17595995 | 0.83 | MEN1 (0.45) | HDAC8MEN1KMT2ACA2CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108367043-A | The conjugate of quaternized tubulysin compound | 西雅图基因公司 | 2018-08-03 | — | — | CN | disclosed |