Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27722468 | 0.98 | TSHR (0.42) | TSHRALDH1A1CYP3A4LPAR2LPAR3 | |
| SCHEMBL28176947 | 0.93 | TSHR (0.41) | TSHRALDH1A1CYP3A4LPAR2LPAR3 | |
| SCHEMBL93378 | 0.87 | TSHR (0.50) | TSHRALDH1A1CYP3A4LPAR2LPAR3 | |
| SCHEMBL28186307 | 0.86 | TSHR (0.48) | TSHRALDH1A1CYP3A4LPAR2LPAR3 | |
| SCHEMBL27507990 | 0.83 | TSHR (0.55) | TSHRALDH1A1CYP3A4LPAR2LPAR3 | |
| Acrylamide SCHEMBL28209416 | 0.81 | TSHR (0.44) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL28109970 | 0.81 | TSHR (0.40) | TSHRALDH1A1CYP3A4LPAR2LPAR3 | |
| SCHEMBL28200930 | 0.80 | LPAR3 (0.53) | TSHRALDH1A1CYP3A4LPAR2LPAR3 | |
| SCHEMBL27821410 | 0.80 | TSHR (0.39) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL28433337 | 0.79 | TSHR (0.53) | TSHRALDH1A1CYP3A4LPAR2LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108853607-A | A kind of insulin needle surface siliconization inorganic agent | 广州市爱创医疗科技有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-108473484-A | Compounds useful as TRPM8 modulators | 赛诺米克斯公司 | 2018-08-31 | — | — | CN | disclosed |