Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | GLI1 | P08151 | 1/20 | 0.37 |
| ▸ | GLI2 | P10070 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10835752 | 0.77 | — | — | |
| SCHEMBL3480456 | 0.74 | — | — | |
| SCHEMBL11507660 | 0.71 | — | — | |
| SCHEMBL789243 | 0.69 | — | — | |
| SCHEMBL27646239 | 0.69 | — | — | |
| SCHEMBL30019197 | 0.68 | — | — | |
| SCHEMBL22928577 | 0.67 | — | — | |
| SCHEMBL2697434 | 0.67 | — | — | |
| SCHEMBL13862475 | 0.67 | — | — | |
| SCHEMBL879175 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341814-A | Jak kinase inhibitor and its application | 上海翔锦生物科技有限公司 | 2018-07-31 | — | — | CN | disclosed |