SCHEMBL28237697

SCHEMBL28237697

N#CC1(NC2CC[CH]CC2)CCC1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.34
PDE4A P27815 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25217906 0.86 PDE4A (0.39) CYP1A2PDE4A
SCHEMBL12457344 0.82 PDE4A (0.43) CYP1A2PDE4A
SCHEMBL75352 0.81 PDE4A (0.42) CYP1A2PDE4A
SCHEMBL77203 0.79 PDE4A (0.45) CYP1A2PDE4A
SCHEMBL24230067 0.79 PDE4A (0.45) CYP1A2PDE4A
SCHEMBL11318852 0.78 PDE4A (0.46) CYP1A2PDE4A
SCHEMBL19228803 0.77 PDE4A (0.35) CYP1A2PDE4A
SCHEMBL19128044 0.72 KMT2A (0.33) PDE4A
SCHEMBL19147576 0.69 HRH1 (0.41)
SCHEMBL19228802 0.69 HRH1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108473471-A Substituted thiourocystine derivatives as androgen receptor antagonists 詹森药业有限公司 2018-08-31 CN disclosed