Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 5/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL463304 | 0.79 | SLC22A6 (0.53) | SLC22A6ATMHTR2CHTR2AHTR2B | |
| SCHEMBL27769668 | 0.70 | SLC22A6 (0.54) | SLC22A6ATMMEN1CYP3A4MAPT | |
| SCHEMBL28174322 | 0.68 | NCOA1 (0.44) | HTR2AMEN1CYP3A4MAPTKMT2A | |
| SCHEMBL3538344 | 0.66 | SLC22A6 (0.58) | SLC22A6ATMHTR2CHTR2AHTR2B | |
| SCHEMBL6535531 | 0.66 | SLC22A6 (0.58) | SLC22A6ATMHTR2CHTR2AHTR2B | |
| SCHEMBL27791302 | 0.66 | HTR2C (0.56) | KCNA3HTR2CHTR2AHTR2BADRB2 | |
| SCHEMBL1899742 | 0.63 | SLC22A6 (0.59) | SLC22A6ATMMEN1CYP3A4MAPT | |
| SCHEMBL28961088 | 0.63 | SLC22A6 (0.55) | SLC22A6ATMHTR2CHTR2AHTR2B | |
| SCHEMBL28374800 | 0.63 | SLC22A6 (0.55) | SLC22A6ATMHTR2CHTR2AHTR2B | |
| SCHEMBL28459212 | 0.63 | SLC22A6 (0.59) | SLC22A6ATMMEN1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484608-A | A kind of Pyrazolopyrimidine compound and application thereof and luminescent device | 上海道亦化工科技有限公司 | 2018-09-04 | — | — | CN | disclosed |