Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5306721 | 1.00 | TSHR (0.58) | TSHRCA2ZDHHC7FAAHLMNA | |
| SCHEMBL27448354 | 1.00 | TSHR (0.58) | TSHRCA2ZDHHC7FAAHLMNA | |
| SCHEMBL27451160 | 1.00 | TSHR (0.58) | TSHRCA2ZDHHC7FAAHLMNA | |
| SCHEMBL28063217 | 0.93 | TSHR (0.53) | TSHRCA2FAAHLMNACA1 | |
| SCHEMBL28063225 | 0.92 | TSHR (0.51) | TSHRCA2FAAHLMNACA1 | |
| SCHEMBL28546607 | 0.92 | TSHR (0.59) | TSHRCA2ZDHHC7FAAHCA1 | |
| SCHEMBL22598174 | 0.92 | TSHR (0.59) | TSHRCA2ZDHHC7FAAHCA1 | |
| SCHEMBL22598182 | 0.92 | TSHR (0.59) | TSHRCA2ZDHHC7FAAHCA1 | |
| SCHEMBL22598334 | 0.92 | TSHR (0.59) | TSHRCA2ZDHHC7FAAHCA1 | |
| SCHEMBL28545057 | 0.92 | TSHR (0.59) | TSHRCA2ZDHHC7FAAHCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473484-A | Compounds useful as TRPM8 modulators | 赛诺米克斯公司 | 2018-08-31 | — | — | CN | disclosed |