Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.32 |
| ▸ | GOT1 | P17174 | 1/20 | 0.32 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.32 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10246637 | 0.77 | SLC6A2 (0.49) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| SCHEMBL23346884 | 0.77 | SLC6A2 (0.49) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| SCHEMBL431258 | 0.77 | SLC6A2 (0.49) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| SCHEMBL29586069 | 0.77 | SLC6A2 (0.49) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| Hydrochloric Acid SCHEMBL15717047 | 0.76 | SLC6A2 (0.48) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| SCHEMBL18761410 | 0.73 | SLC6A2 (0.46) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| Hydrochloric Acid SCHEMBL15717188 | 0.72 | SLC6A2 (0.44) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| SCHEMBL30574315 | 0.70 | NOTUM (0.55) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| SCHEMBL14275844 | 0.70 | NOTUM (0.55) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| SCHEMBL432343 | 0.70 | SLC6A2 (0.47) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104903310-B | Bicyclic urea, thiourea, guanidine and cyanoguanidine compounds useful for the treatment of pain | 阵列生物制药公司 | 2018-08-14 | — | — | CN | disclosed |