Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16314168 | 0.84 | MAPT (0.53) | MAPTKMT2ACYP2D6CYP1A2CYP2C19 | |
| SCHEMBL28310656 | 0.82 | MAPT (0.52) | MAPTKMT2ACYP2D6CYP1A2CYP2C19 | |
| SCHEMBL13868824 | 0.82 | CYP2D6 (0.50) | MAPTKMT2ACYP2D6CYP1A2CYP2C19 | |
| SCHEMBL29253368 | 0.82 | MAPT (0.55) | MAPTKMT2ACYP2D6CYP1A2CYP2C19 | |
| SCHEMBL616620 | 0.80 | MAPT (0.53) | MAPTKMT2ACYP2D6CYP1A2CYP2C19 | |
| SCHEMBL616399 | 0.78 | MAPT (0.52) | MAPTKMT2ACYP2D6CYP1A2CYP2C19 | |
| SCHEMBL615871 | 0.78 | MAPT (0.52) | MAPTKMT2ACYP2D6CYP1A2CYP2C19 | |
| SCHEMBL5281006 | 0.78 | MAPT (0.55) | MAPTKMT2ACYP2D6CYP1A2CYP2C19 | |
| SCHEMBL18595880 | 0.77 | KMT2A (0.48) | MAPTKMT2ACYP2D6CYP1A2CYP2C19 | |
| SCHEMBL618737 | 0.76 | MAPT (0.48) | MAPTKMT2ACYP2D6CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658803-A | A kind of synthetic method of N, N- dialkyl group diphenylpropanamide | 青岛科技大学 | 2018-10-16 | — | — | CN | disclosed |