Chloromethane

Chloromethane

SCHEMBL28239478

CCl.O=C(O)C(Cc1ccccc1)N(O)O

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.52
ADAMTS5 Q9UNA0 2/20 0.49
SLC1A3 P43003 1/20 0.49
SLC1A2 P43004 1/20 0.49
SLC1A1 P43005 1/20 0.49
ALPI P09923 1/20 0.48
PKM P14618 1/20 0.48
PTGS1 P23219 1/20 0.48
XIAP P98170 1/20 0.48
SLC7A5 Q01650 1/20 0.48
MAPT P10636 2/20 0.46
ALDH1A1 P00352 1/20 0.46
CPA1 P15085 3/20 0.46
CPA3 P15088 2/20 0.46
FOLH1 Q04609 1/20 0.46
CPB1 P15086 1/20 0.46
CPB2 Q96IY4 1/20 0.46
HSD17B10 Q99714 2/20 0.45
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL157789 0.94 CYP1A2 (0.57) CYP1A2SLC1A3SLC1A2SLC1A1ALPI
SCHEMBL2466759 0.94 CYP1A2 (0.57) CYP1A2SLC1A3SLC1A2SLC1A1ALPI
SCHEMBL157788 0.94 CYP1A2 (0.57) CYP1A2SLC1A3SLC1A2SLC1A1ALPI
Ammonia Solution, Strong SCHEMBL8346946 0.92 CYP1A2 (0.55) CYP1A2ADAMTS5SLC1A3SLC1A2SLC1A1
Water SCHEMBL28204086 0.92 CYP1A2 (0.55) CYP1A2ADAMTS5SLC1A3SLC1A2SLC1A1
SCHEMBL27996592 0.92 CYP1A2 (0.55) CYP1A2ADAMTS5SLC1A3SLC1A2SLC1A1
Diphenylmethane SCHEMBL27627447 0.89 CYP1A2 (0.52) CYP1A2SLC1A3SLC1A2SLC1A1ALPI
Phosphoric Acid SCHEMBL28045535 0.87 CYP1A2 (0.50) CYP1A2SLC1A3SLC1A2SLC1A1ALPI
Phenol SCHEMBL27420281 0.87 CYP1A2 (0.50) CYP1A2ADAMTS5SLC1A3SLC1A2SLC1A1
Methacrylic Acid SCHEMBL27879874 0.86 ALPI (0.47) CYP1A2ADAMTS5SLC1A3SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102274517-B The method for treating Parkinson's disease 纽朗制药公司 2018-08-31 CN disclosed