Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | HTR5A | P47898 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29384370 | 0.78 | PDK2 (0.42) | PDK2PDK4KDM1AHTR5AATM | |
| SCHEMBL1031209 | 0.78 | PDK2 (0.42) | PDK2PDK4KDM1AHTR5AATM | |
| Hydrochloric Acid SCHEMBL2482151 | 0.77 | PDK2 (0.41) | PDK2PDK4KDM1AHTR5AATM | |
| SCHEMBL24124146 | 0.75 | PDK2 (0.39) | PDK2PDK4KDM1AHTR5AATM | |
| SCHEMBL2349269 | 0.75 | PDK2 (0.39) | PDK2PDK4KDM1AHTR5AATM | |
| SCHEMBL27491877 | 0.73 | KDM1A (0.40) | PDK2PDK4KDM1AHTR5AATM | |
| SCHEMBL26295503 | 0.72 | PDK2 (0.37) | PDK2PDK4KDM1AHTR5AATM | |
| SCHEMBL16566109 | 0.72 | KDM1A (0.39) | PDK2PDK4KDM1AHTR5AATM | |
| SCHEMBL20506223 | 0.71 | BRD4 (0.37) | PDK2PDK4KDM1AHTR5AATM | |
| SCHEMBL1094251 | 0.71 | PDK2 (0.40) | PDK2PDK4KDM1AHTR5AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108495855-A | Condesned thiazole and pyrimidine derivatives as MNK inhibitor | 生命弧度公司 | 2018-09-04 | — | — | CN | disclosed |