Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 15/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2824205 | 0.92 | DHODH (0.70) | DHODHMEN1TSHRKMT2ATP53 | |
| SCHEMBL468612 | 0.90 | DHODH (0.72) | DHODHMEN1TSHRKMT2ATP53 | |
| SCHEMBL2407460 | 0.88 | DHODH (0.59) | DHODHMEN1TSHRKMT2ATP53 | |
| SCHEMBL3665369 | 0.87 | DHODH (0.63) | DHODHMEN1TSHRKMT2ATP53 | |
| SCHEMBL468516 | 0.80 | DHODH (0.65) | DHODH | |
| SCHEMBL2404091 | 0.80 | DHODH (0.52) | DHODH | |
| SCHEMBL15789954 | 0.78 | DHODH (0.71) | DHODHTP53MAPT | |
| SCHEMBL2407162 | 0.78 | DHODH (0.54) | DHODH | |
| SCHEMBL15789789 | 0.77 | DHODH (0.65) | DHODHMEN1TSHRKMT2ATP53 | |
| SCHEMBL468857 | 0.77 | DHODH (1.00) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178840-A1 | AZABIPHENYLAMINOBENZOIC ACID DERIVATIVES AS DHODH INHIBITORS | Almirall, S.A. (ES) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009021696-A1 | AZABIPHENYLAMINOBENZOIC ACID DERIVATIVES AS DHODH INHIBITORS | ALMIRALL, S.A. (ES) | 2009-02-19 | — | — | WO | disclosed |